Chemical Proteomics Technology
Compounds are tethered to a solid support using special linkers to capture specific interacting protein targets from cells or tissues.
The genuine protein target(s) are then identified by mass spectrometric analysis.
The results of all experiments can be rapidly gauged against Cellzome's extensive proteomics data set for the identification of target-lead-pairs.
The method is fast and efficient for the identification of protein binders from any subcellular compartment and from cells and tissues alike.

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purification of drug binding protein
ms protein identification
bioinformatic annotation
lead-target pair

