Cellzome's product engine is employed both in house and in partnered drug discovery. The engine encompasses key proprietary technologies, Episphere™ and Kinobeads™ which work with native proteins in a true physiological setting to discover small molecule drugs targeting protein complexes that underlie disease.
Cellzome's in house drug discovery focuses on epigenetic and signal transduction (kinase) drug targets in inflammation and cancer, but it can also be applied in other disease indications.
Cellzome identifies compounds which target not only the correct enzyme, but the correct complex, leading to more precise drug candidates for cancer and inflammation using Episphere™ technology.
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Cellzome pursues several kinase programmes, where the Kinobeads™ technology is essential to design potent and selective inhibitors. Read more...